People 65 years of age and older should get the flu shot in particular because they are more likely to experience significant flu complications. People 65 years of age and older are advised to get three particular flu shots over others.
According to the CDC, flu vaccines with greater doses or adjuvants, such as Fluzone High-Dose Quadrivalent, Flublok Quadrivalent, or Fluad Quadrivalent, should be administered to people 65 and older. These vaccines are preferred for those 65 years of age and older since a review of prior research indicated that they may be more effective in this age group than regular dosage unadjuvanted flu vaccines.
For the 2022–2023 flu season, the CDC recommends that older adults (65 and older) get higher-dose or adjuvanted flu vaccines (Fluzone High-Dose Quadrivalent inactivated influenza vaccine and Flublok Quadrivalent vaccine) rather than standard-dose unadjuvanted flu vaccines.
This advice is based on an assessment of the studies that are currently available and indicates that these vaccines may be more effective than standard dosage unadjuvanted flu vaccines in this age range.
People in this age range should get a standard-dose unadjuvanted inactivated influenza vaccination in the event that one of these vaccines is not available at the time of administration. There are other flu vaccines that can be used on older adults (65 and older). Nasal spray vaccinations shouldn't be given to people over 65.
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